Redox Flavin
An adaptive redox regulation hypothesis for neurodegenerative disease.
Core idea: restore neuronal redox self-regulation (homeostatic governance) rather than compensate with static supplementation.
This site provides a concise research-facing overview, a technical white paper, and an experimental roadmap designed for rigorous validation or falsification.
This project is a hypothesis and does not claim clinical validation or therapeutic efficacy.
What is being proposed?
A flavin-based regulatory protein architecture (RFR) integrating: (1) redox sensing, (2) control logic with hysteresis/integration, (3) endogenous program activation, and (4) shutdown once homeostasis returns.
Why now?
Alzheimer’s pathology is increasingly linked to mitochondrial dysfunction and redox drift. Existing approaches often buffer oxidative damage but may not restore adaptive control of redox balance.
How is it tested?
A staged MVP roadmap (MVP-0 to MVP-4) that incrementally validates sensor behavior, mitochondrial response, neuronal function, adaptive mitophagy, and safety/specificity.